2026 USCAP Hematopathology Update

Complete Video Course + PDFs | Advanced Hematopathology Education

Stay current with modern hematopathology through the 2026 USCAP Hematopathology Update, an advanced educational program covering the diagnosis, classification, and interpretation of lymphoid, myeloid, and other hematopoietic disorders.

Designed for practicing pathologists, hematopathologists, residents, fellows, and other physicians involved in hematologic diagnosis, this comprehensive course combines morphology, immunophenotyping, molecular diagnostics, cytogenetics, and contemporary classification systems to provide a practical update on today’s diagnostic hematopathology.

Course Information

Organization: United States and Canadian Academy of Pathology (USCAP)
Original Release Date: August 1, 2026
Format: Video Presentations + Course PDFs/Documents
Specialty: Pathology • Hematopathology • Hematology
Official Course CME: 24 AMA PRA Category 1 Credits™

What You’ll Learn

The program provides extensive coverage of both lymphoid and myeloid pathology, with particular emphasis on applying the WHO Classification of Haematolymphoid Tumours, 5th Edition and the International Consensus Classification (ICC) to real-world diagnostic practice.

Through expert-led presentations, you’ll strengthen your ability to:

• Recognize key morphologic features of common and uncommon hematolymphoid neoplasms.
• Distinguish reactive and non-neoplastic processes from hematologic malignancies.
• Apply updated WHO 5th Edition and ICC diagnostic criteria.
• Understand important differences between WHO and ICC classifications.
• Select appropriate ancillary studies based on morphology and clinical findings.
• Interpret immunophenotypic, molecular, cytogenetic, and other diagnostic results.
• Integrate morphology and ancillary testing into a comprehensive final diagnosis.
• Evaluate challenging treated, progressed, and diagnostically complex cases.

Comprehensive Hematopathology Coverage

Lymphoid Pathology

Explore the diagnostic approach to:

Reactive Lymphadenopathies • Plasma Cell Neoplasms • CLL/SLL • Mantle Cell Lymphoma • Hairy Cell Leukemia • Splenic Marginal Zone Lymphoma • Lymphoplasmacytic Lymphoma • Richter Transformation • Follicular Lymphoma • Nodal Marginal Zone Lymphoma • Extranodal Lymphomas • Burkitt Lymphoma • High-Grade B-Cell Lymphomas • DLBCL • Hodgkin Lymphoma • Peripheral T-Cell Lymphomas • Cutaneous B- and T-Cell Lymphomas • Immunodeficiency-Associated Lymphoproliferations

Myeloid & Bone Marrow Pathology

Develop an updated understanding of:

Acute Myeloid Leukemia (AML) • Myelodysplastic Neoplasms • Clonal Cytopenias • Myeloproliferative Neoplasms • MDS/MPN Disorders • Pediatric Myeloid Neoplasms • Germline Predisposition Conditions • Systemic Mastocytosis • Eosinophilic Neoplasms • Mixed Phenotype Acute Leukemia • Treated and Progressed Myeloid Neoplasms • Non-Neoplastic Bone Marrow Disorders

Additional Advanced Topics

The program also addresses:

B- and T-Lymphoblastic Leukemia/Lymphoma • Histiocytic and Dendritic Neoplasms • Molecular Hematopathology • Ancillary Testing • WHO 5th Edition • ICC Classification • Diagnostic Pitfalls • Expert Panel Q&A

Complete Course Program

1. Reactive Lymph Nodes

Amy Chadburn, MD
Review reactive lymphadenopathies and important morphologic patterns that may mimic hematolymphoid neoplasia.

2. Plasma Cell Neoplasms

Robert Lorsbach, MD, PhD
Diagnostic evaluation and modern classification of plasma cell disorders and neoplasms.

3. Bone Marrow B-Cell Lymphomas

Laurence L. de Leval, MD, PhD
Coverage of CLL, mantle cell lymphoma, hairy cell leukemia, splenic marginal zone lymphoma, lymphoplasmacytic lymphoma, SLL, and Richter transformation.

4. Follicular & Nodal Marginal Zone Lymphomas

Ioannis Anagnostopoulos, MD
Morphologic features, differential diagnosis, and classification.

5. Extranodal B-Cell & Splenic Lymphomas

Judith A. Ferry, MD
Diagnostic strategies for extranodal and splenic B-cell neoplasms.

6. Burkitt, High-Grade Lymphoma & DLBCL

Amy Chadburn, MD
An advanced review of Burkitt lymphoma, high-grade B-cell lymphoma, and diffuse large B-cell lymphoma.

7. The Many Other Faces of DLBCL

Judith A. Ferry, MD
Challenging presentations, variants, and important diagnostic considerations.

8. Hodgkin Lymphoma & Related Entities

Ioannis Anagnostopoulos, MD
Current criteria and differential diagnosis of Hodgkin lymphoma and related disorders.

9. Immunodeficiency & Fluid-Based B-Cell Lymphomas

Amy Chadburn, MD
Review of immunodeficiency-associated proliferations and fluid-based lymphoma entities.

10–11. Peripheral T-Cell Lymphomas

Laurence L. de Leval, MD, PhD
Two dedicated sessions covering morphology, classification, and differential diagnosis of peripheral T-cell lymphomas.

12. Cutaneous T-Cell & B-Cell Lymphomas

Judith A. Ferry, MD
Diagnostic evaluation of primary cutaneous lymphoid neoplasms.

13. Non-Neoplastic Bone Marrow Conditions

Robert P. Hasserjian, MD
Morphologic evaluation of reactive and non-neoplastic bone marrow abnormalities.

14. Myeloproliferative Neoplasms

Daniel A. Arber, MD
Updated diagnostic criteria and classification of myeloproliferative neoplasms.

15. Myelodysplastic Neoplasms & Clonal Cytopenias

Robert P. Hasserjian, MD
Contemporary approaches to MDS and clonal cytopenic disorders.

16. Pediatric Myeloid Neoplasms & Germline Conditions

Robert Lorsbach, MD, PhD
Pediatric myeloid malignancies and hereditary predisposition disorders.

17. Acute Myeloid Leukemia

Joseph D. Khoury, MD
Modern AML classification incorporating morphology, immunophenotyping, and molecular findings.

18. B- & T-Lymphoblastic Leukemia/Lymphoma

Robert Lorsbach, MD, PhD
Diagnostic approach to B- and T-lineage lymphoblastic neoplasms.

19. Histiocytic & Dendritic Neoplasms

Joseph D. Khoury, MD
Classification and differential diagnosis of histiocytic and dendritic-cell neoplasms.

20. Mixed Phenotype Acute Leukemias & Eosinophilic Neoplasms

Joseph D. Khoury, MD
Review of mixed phenotype acute leukemia and neoplasms associated with eosinophilia.

21. Systemic Mastocytosis

Daniel A. Arber, MD
Current criteria and classification of systemic mastocytosis.

22. MDS/MPN

Daniel A. Arber, MD
Morphologic and molecular evaluation of overlapping myelodysplastic/myeloproliferative neoplasms.

23. Progressed & Treated Myeloid Neoplasms

Robert P. Hasserjian, MD
Assessment of disease progression, treatment effects, and post-treatment bone marrow findings.

24. Expert Panel Q&A

Practical discussions addressing challenging hematopathology cases and diagnostic questions.

Why Study This Update?

Hematopathology is rapidly evolving as molecular testing and next-generation sequencing become increasingly integrated into routine diagnostic practice.

Yet morphologic interpretation remains fundamental.

Accurate morphology helps determine which ancillary studies are appropriate and provides the framework needed to interpret molecular, immunophenotypic, cytogenetic, and clinical findings correctly.

The 2026 USCAP Hematopathology Update bridges these areas by combining traditional morphologic expertise with contemporary molecular diagnostics and modern classification systems.

Who Is This Course For?

This program is particularly relevant for:

Practicing Pathologists • Hematopathologists • Academic Pathologists • Community Pathologists • Pathology Residents • Pathology Fellows • Hematopathology Fellows • Hematologists • Physicians Reviewing Hematopathology • Board and Continuing-Certification Learners

Key Benefits

✓ Comprehensive Video Education — Learn through expert-led hematopathology presentations.

✓ PDF Course Materials — Accompany the lectures with useful educational documents.

✓ Updated Classification — Review both WHO 5th Edition and ICC frameworks.

✓ Lymphoid + Myeloid Coverage — Study a broad spectrum of hematolymphoid disorders in one program.

✓ Modern Diagnostic Approach — Connect morphology with immunophenotyping, molecular testing, cytogenetics, and clinical information.

✓ Expert Faculty — Learn from experienced specialists in contemporary hematopathology.

2026 USCAP Hematopathology Update

Videos + PDFs • Advanced Diagnostic Hematopathology • WHO 5th Edition • ICC • Lymphoma • Leukemia • Bone Marrow Pathology • Molecular Diagnostics

A comprehensive educational resource for pathology professionals seeking an up-to-date review of modern hematopathology diagnosis and classification.